欲了解更多信息,請(qǐng)點(diǎn)擊此處聯(lián)系我們,或通過郵箱tech@sbsbio.com與我們?nèi)〉寐?lián)系。
介紹
IDH1(異檸檬酸脫氫酶1,IDH1)突變可在膠質(zhì)母細(xì)胞瘤和骨髓增殖性腫瘤中發(fā)現(xiàn)。IDH1突變檢測(cè)可以作為預(yù)后的積極預(yù)測(cè)因子和膠質(zhì)母細(xì)胞瘤患者的分子標(biāo)志物。另一方面,據(jù)報(bào)道,IDH1突變與骨髓增殖性腫瘤的不良預(yù)后相關(guān)。
總共可以檢測(cè)和區(qū)分 5 種 IDH1 突變
Mutations突變 | Size規(guī)格 |
Codon 132 | 25 tests |
5 |
特點(diǎn)
高靈敏度和特異性,即使是少量DNA(1%檢測(cè)下限,使用10 ng的野生型/突變型混合DNA)
基于實(shí)時(shí)PCR的即用型試劑盒
短運(yùn)行時(shí)間(3小時(shí)內(nèi))
流程
樣本準(zhǔn)備
總DNA提取
實(shí)時(shí)PCR
結(jié)果分析
兼容樣本類型
FFPE 組織
新鮮組織
兼容的實(shí)時(shí)PCR設(shè)備
CFX96 (Bio-Rad)
Rotor-Gene Q (Qiagen)
ABI7500 (Thermo Fisher Scientific)
LightCycler 480II (Roche)
精選引用
想了解使用我們的PNA已發(fā)表的研究文獻(xiàn)嗎?
Exponential Increase in an Ionic Signal: A Dominant Role of the Space Charge Effect on the Outer Surface of Nanochannels
Anal. Chem. | 28 Sep 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c03431
All single-stranded PNA sequences were purchased from SBS Genetech Co., Ltd. (Beijing, China).
Peptide Nucleic Acid-Functionalized Nanochannel Biosensor for the Highly Sensitive Detection of Tumor Exosomal MicroRNA
Anal. Chem. | 30 July 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c01898
PNA was synthesized by SBS Genetech Co. Ltd. (Beijing, China). Table S1 shows the above-mentioned oligonucleotide sequence. Sodium hydroxide (NaOH), formic acid (HCOOH), and other chemical reagents were obtained from Sinopharm Chemical Reagent Co. Ltd. (Shanghai, China).
Ultrasensitive Exosomal MicroRNA Detection with a Supercharged DNA Framework Nanolabel
Anal. Chem. | 2 April 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c00295
Thiolated PNA with a−(CH2)6− spacer at the 5′ end was synthesized and purified by SBS Genetech Co., Ltd. (Beijing, China). All the sequences
are shown in Table S1.
僅用于研究,不用于治療人類或動(dòng)物
使用賽百盛產(chǎn)品所發(fā)表的期刊 使用賽百盛產(chǎn)品的大學(xué)與機(jī)構(gòu)
北京賽百盛基因技術(shù)有限公司是冷泉港實(shí)驗(yàn)室的長期贊助合作伙伴