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介紹
C-kit(也稱為CD117)可能在某些類型的癌細胞中(包括胃腸道間質(zhì)瘤和黑色素瘤)以高于正常的量或變化的形式出現(xiàn)。測量腫瘤組織中的C-kit量可能有助于診斷癌癥和制定治療計劃。C-kit是一種受體酪氨酸激酶和腫瘤標志物。
總共可以檢測到 5 種 c-KIT
Mutations突變 | Size規(guī)格 |
Codon 816 | 25 tests |
5 |
特點
高靈敏度和特異性,即使是少量DNA(2%檢測下限,使用10 ng的野生型/突變型混合DNA)
基于實時PCR的即用型試劑盒
短運行時間(3小時內(nèi))
流程
樣本準備
總DNA提取
實時PCR
結(jié)果分析
兼容樣本類型
FFPE組織
活檢組織
兼容的實時PCR設(shè)備
CFX96 (Bio-Rad)
QuantStudio5 (Thermo Fisher Scientific)
LightCycler 480II (Roche)
ABI7500 (Thermo Fisher Scientific)
ABI7900HT (Thermo Fisher Scientific)
StepOnePlus (Thermo Fisher Scientific)
Rotor-Gene Q (Qiagen)
精選引用
想了解使用我們的PNA已發(fā)表的研究文獻嗎?
Exponential Increase in an Ionic Signal: A Dominant Role of the Space Charge Effect on the Outer Surface of Nanochannels
Anal. Chem. | 28 Sep 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c03431
All single-stranded PNA sequences were purchased from SBS Genetech Co., Ltd. (Beijing, China).
Peptide Nucleic Acid-Functionalized Nanochannel Biosensor for the Highly Sensitive Detection of Tumor Exosomal MicroRNA
Anal. Chem. | 30 July 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c01898
PNA was synthesized by SBS Genetech Co. Ltd. (Beijing, China). Table S1 shows the above-mentioned oligonucleotide sequence. Sodium hydroxide (NaOH), formic acid (HCOOH), and other chemical reagents were obtained from Sinopharm Chemical Reagent Co. Ltd. (Shanghai, China).
Ultrasensitive Exosomal MicroRNA Detection with a Supercharged DNA Framework Nanolabel
Anal. Chem. | 2 April 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c00295
Thiolated PNA with a−(CH2)6− spacer at the 5′ end was synthesized and purified by SBS Genetech Co., Ltd. (Beijing, China). All the sequences
are shown in Table S1.
僅用于研究,不用于治療人類或動物
使用賽百盛產(chǎn)品所發(fā)表的期刊 使用賽百盛產(chǎn)品的大學(xué)與機構(gòu)
北京賽百盛基因技術(shù)有限公司是冷泉港實驗室的長期贊助合作伙伴