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介紹
憑借 肽核酸(PNA) 的獨特優(yōu)勢,PNA miRNA 抑制劑在特異性和穩(wěn)定性方面遠勝于現(xiàn)有的 miRNA 抑制劑。這些單鏈 PNA 是研究 miRNA 功能的絕佳工具,通過特異性結(jié)合內(nèi)源性 miRNA,有效抑制其功能。
此外,PNA miRNA 抑制劑結(jié)合了 CPP(細胞穿透肽),不僅提升了轉(zhuǎn)染效率,甚至在某些細胞類型中無需轉(zhuǎn)染試劑即可實現(xiàn)穿透。
產(chǎn)品名稱 | 序列 | 規(guī)格 |
GR PNA-L | Lys-TAACGGTATTTGGAG-Lys | 3 nmole |
Lys-GTAGTTGGACTTAGG-Lys | ||
Lys-GCCCTTCATAATATC-Lys | ||
Lys-ATCCAGATGCTCAAG-Lys | ||
GR PNA-L | Lys-TAACGGTATTTGGAG-Lys | 10 nmole |
Lys-GTAGTTGGACTTAGG-Lys | ||
Lys-GCCCTTCATAATATC-Lys | ||
Lys-ATCCAGATGCTCAAG-Lys |
精選引用
想了解使用我們的PNA已發(fā)表的研究文獻嗎?
Exponential Increase in an Ionic Signal: A Dominant Role of the Space Charge Effect on the Outer Surface of Nanochannels
Anal. Chem. | 28 Sep 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c03431
All single-stranded PNA sequences were purchased from SBS Genetech Co., Ltd. (Beijing, China).
Peptide Nucleic Acid-Functionalized Nanochannel Biosensor for the Highly Sensitive Detection of Tumor Exosomal MicroRNA
Anal. Chem. | 30 July 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c01898
PNA was synthesized by SBS Genetech Co. Ltd. (Beijing, China). Table S1 shows the above-mentioned oligonucleotide sequence. Sodium hydroxide (NaOH), formic acid (HCOOH), and other chemical reagents were obtained from Sinopharm Chemical Reagent Co. Ltd. (Shanghai, China).
Ultrasensitive Exosomal MicroRNA Detection with a Supercharged DNA Framework Nanolabel
Anal. Chem. | 2 April 2021 | DOI: https://doi.org/10.1021/acs.analchem.1c00295
Thiolated PNA with a−(CH2)6− spacer at the 5′ end was synthesized and purified by SBS Genetech Co., Ltd. (Beijing, China). All the sequences
are shown in Table S1.
僅用于研究,不用于治療人類或動物
使用賽百盛產(chǎn)品所發(fā)表的期刊 使用賽百盛產(chǎn)品的大學(xué)與機構(gòu)
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